PROTAC ERα Degrader-4 - HY-149295
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Catalog #
HY-149295
Ab
558,00 €
PROTAC ERα Degrader-4 (Compound ZD12) is a highly potent and selectivePROTAC ERα degrader (Ki: 5.08 μM). PROTAC ERα Degrader-4 contains OBHSAs, linker and E3 ligase ligands. PROTAC ERα Degrader-4 shows excellent cell inhibitory and ERα degradation activity against Tamoxifen-sensitive and -resistant ER+ breast cancer (BC) cells and ERα-mutated BC cells. PROTAC ERα Degrader-4 can induce apoptosis and can be used for cancer research.
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-149295/PROTAC-ERα-Degrader-4-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| CAS | 2521299-80-7 |
| Storage | -20°C, 3 years (Powder) |
| MWT | 1074.23 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Apoptosis;Estrogen Receptor/ERR;PROTACs |
| Application: | Cancer-programmed cell death |
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