PROTAC GSK-3β Degrader-1 - HY-149845
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Catalog #
HY-149845
Ab
449,00 €
PROTAC GSK-3β Degrader-1 (compound 1) is a degrader targets GSK-3β degradation with an IC50 value of 833 nM. PROTAC GSK-3β Degrader-1 contains SB-216763 (a GSK-3β inhibitor), a PEG linker and a CRBN (E3 ligase liand). PROTAC GSK-3β Degrader-1 reduces the neurotoxicity induced by Aβ25-35 peptide and CuSO4. PROTAC GSK-3β Degrader-1 can be used to research in Alzheimer's disease[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-149845/PROTAC-GSK-3β-Degrader-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Neuroscience-Neurodegeneration |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 857.73 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | GSK-3;PROTACs |
| Application: | Neuroscience-Neurodegeneration |
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