S-Methyl-N,N-diethylthiolcarbamate - HY-151229
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Catalog #
HY-151229
Ab
72,00 €
S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) is the active metabolite of the aldehyde dehydrogenase inhibitor disulfiram (HY-B0240). It is produced by the methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) inhibits rat liver low Km aldehyde dehydrogenase (ALDH) (ID50=15.5 mg/kg). When administered at a dose of 20.6 mg/kg, it decreases mean arterial pressure (MAP) and increases heart rate in rats during ethanol stimulation.
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-151229/S-Methyl-N-N-diethylthiolcarbamate-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Metabolism-sugar/lipid metabolism |
| Alternative Names | DETC-Me; DDTC-Me; Diethyldithiocarbamic acid methyl ester |
| CAS | 686-07-7 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 163.30 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Aldehyde Dehydrogenase (ALDH) |
| Application: | Metabolism-sugar/lipid metabolism |
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