NADPH oxidase-IN-1 - HY-152026
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Catalog #
HY-152026
Ab
155,00 €
NADPH oxidase-IN-1 is an orally active NADPH oxidase (Nox) inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier (BBB), inhibits Nox2 and Nox4 with IC50s of 1.9 μM and 2.47 μM, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-152026/NADPH-oxidase-IN-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Neuroscience-Neurodegeneration |
| CAS | 2762405-17-2 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 373.51 |
| Solubility | DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | No Development Reported |
| Target | NADPH Oxidase |
| Application: | Neuroscience-Neurodegeneration |
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