PROTAC EZH2 Degrader-2 - HY-157164
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Catalog #
HY-157164
Ab
333,00 €
PROTAC EZH2 Degrader-2 (compound E-3P-MDM2), an EZH2 inhibitor, is a PROTAC composed of Tazemetostat (EPZ6438) and an E3 ligase system ligand. PROTAC EZH2 Degrader-2 degrades EZH2 in SU-DHL-6 cells in a dose-dependent manner, inhibits the expression of H3K27me3, and simultaneously degrades EED and SUZ12 proteins without affecting their mRNA levels. PROTAC EZH2 Degrader-2 has anti-cancer and anti-proliferative activity[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-157164/PROTAC-EZH2-Degrader-2-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| Storage | 4°C (Powder, stored under nitrogen) |
| MWT | 1463.55 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Histone Methyltransferase;PROTACs |
| Application: | Cancer-programmed cell death |
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