PROTAC BET Degrader-12 - HY-158764
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Catalog #
HY-158764
Ab
568,00 €
PROTAC BET Degrader-12 (Compound 8b) is a PROTAC degrader for bromodomain and extra-terminal domain (BET)-containing proteins, which degrades the BRD3 and BRD4 in a DCAF11-dependent manner. PROTAC BET Degrader-12 inhibits cell viability of KBM7 with a DC50 of 305.2 nM. (Pink: ligand for target protein (+)-JQ-1 (HY-13030); Black: linker (HY-159077); Blue: ligand for E3 ligase (HY-159076))[1]
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-158764/PROTAC-BET-Degrader-12-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| Storage | 4°C (Powder, protect from light) |
| MWT | 867.46 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Epigenetic Reader Domain;PROTACs |
| Application: | Cancer-programmed cell death |
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