Voxtalisib - HY-15900

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Catalog #
HY-15900
Ab 95,00 €
Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-15900/Voxtalisib-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-Kinase/protease
Alternative Names XL765; SAR245409
CAS 934493-76-2
Storage -20°C, 3 years; 4°C, 2 years (Powder)
MWT 270.29
Solubility DMSO : 10 mg/mL (ultrasonic)
Clinical Information Phase 2
Target mTOR;PI3K
Applications
Application: Cancer-Kinase/protease

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