PROTAC K-Ras Degrader-4 - HY-159788
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Catalog #
HY-159788
Ab
504,00 €
PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway[1]. (Pink: ligand for target protein pan-KRAS degrader 1 (HY-162960); Black: linker (HY-159790); Blue: ligand for E3 ligase VHL (HY-W998248))
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-159788/PROTAC-K-Ras-Degrader-4-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| CAS | 2938169-99-2 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 989.22 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | PROTACs;Ras |
| Application: | Cancer-Kinase/protease |
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