Forodesine (hydrochloride) - HY-16209
Nur noch %1 verfügbar
Catalog #
HY-16209
Ab
57,00 €
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-16209/Forodesine-hydrochloride-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| Alternative Names | BCX-1777 (hydrochloride); Immucillin-H (hydrochloride) |
| CAS | 284490-13-7 |
| Storage | -20°C (Powder, stored under nitrogen, away from moisture) |
| MWT | 302.7142 |
| Solubility | DMSO : 10 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic) |
| Clinical Information | Launched |
| Target | Apoptosis;Nucleoside Antimetabolite/Analog |
| Application: | Cancer-programmed cell death |
|---|