PROTAC NCOA4 degrader-1 - HY-163897
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Catalog #
HY-163897
Ab
992,00 €
PROTAC NCOA4 degrader-1 (Compound V3) is a PROTAC NCOA4 degrader (DC50: 3 nM in HeLa cells). PROTAC NCOA4 degrader-1 is a ferroptosis inhibitor. PROTAC NCOA4 degrader-1 reduces NCOA4 levels and downregulates intracellular ferrous iron (Fe2+) levels. PROTAC NCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model. (Red: NCOA4 ligand (HY-149457). Black: linker (HY-163903). Blue: VHL ligand (HY-138678B))[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-163897/PROTAC-NCOA4-degrader-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | COVID-19-immunoregulation |
| Storage | 4°C (Powder, protect from light, stored under nitrogen) |
| MWT | 1141.43 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Ferroptosis;PROTACs |
| Application: | COVID-19-immunoregulation |
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