PROTAC HDAC6 degrader 3 - HY-171140

PROTAC HDAC6 degrader 3 (Compound 4) is a selective inhibitor and degrader for HDAC6 with an IC50 of 686 nM and a DC50 of 171 nM. PROTAC HDAC6 degrader 3 promotes the acetylation of α-tubulin[1]. (Pink: ligand for target protein (HY-171141); Blue: ligand for E3 ligase VHL (HY-150803))