PROTAC SMARCA2/4 degrader-38 - HY-173333
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Catalog #
HY-173333
Ab
444,00 €
PROTAC SMARCA2/4 degrader-38 is a degrader SMARCA2/4 PROTAC (DC50: 3.0 nM and 4.0 nM respectively). PROTAC SMARCA2/4 degrader-38 promotes the ubiquitination and degradation of SMARCA2/4. PROTAC SMARCA2/4 degrader-38 blocks the G0/G1 cell cycle and induces apoptosis. PROTAC SMARCA2/4 degrader-38 can be used in acute myeloid leukemia (AML) research. (Pink: SMARCA2/4 ligand; Blue: VHL ligand (HY-112078); Black: linker; Target Protein Ligand-Linker Conjugates (HY-173343))[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-173333/PROTAC-SMARCA2-4-degrader-38-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 3081688-77-6 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 773.94 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Apoptosis;Epigenetic Reader Domain;PROTACs |
| Application: | Cancer-programmed cell death |
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