Temozolomide - HY-17364

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Catalog #
HY-17364
Ab 39,00 €
Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-17364/Temozolomide-DataSheet-MedChemExpress.pdf
Shipping Blue Ice
Application Cancer-programmed cell death
Alternative Names NSC 362856; CCRG 81045; TMZ
CAS 85622-93-1
Storage -20°C (Powder, protect from light, stored under nitrogen)
MWT 194.15
Solubility DMSO : 20.83 mg/mL (ultrasonic)|H2O : 2.86 mg/mL (ultrasonic)
Clinical Information Launched
Target Apoptosis;Autophagy;DNA Alkylator/Crosslinker
Applications
Application: Cancer-programmed cell death

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