Itraconazole - HY-17514
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Catalog #
HY-17514
Ab
62,00 €
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor[1][2][3][4].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-17514/Itraconazole-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | COVID-19-immunoregulation |
| Alternative Names | R51211 |
| CAS | 84625-61-6 |
| Storage | 4°C (Powder, protect from light) |
| MWT | 705.63 |
| Solubility | DMSO : 6.25 mg/mL (ultrasonic) |
| Clinical Information | Launched |
| Target | Antibiotic;Autophagy;Bacterial;Cytochrome P450;Fungal;Hedgehog |
| Application: | COVID-19-immunoregulation |
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