PIM-447 (dihydrochloride) - HY-19322B
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Catalog #
HY-19322B
Ab
139,00 €
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-19322B/PIM-447-dihydrochloride-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | LGH447 dihydrochloride |
| CAS | 1820565-69-2 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 513.38 |
| Solubility | DMSO : ≥ 46.7 mg/mL|H2O : 50 mg/mL (ultrasonic) |
| Clinical Information | Phase 1 |
| Target | Apoptosis;Pim |
| Application: | Cancer-Kinase/protease |
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