Pefloxacin-d5 - HY-B0147S
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Catalog #
HY-B0147S
Ab
72,00 €
Pefloxacin-d5 (Pefloxacinium-d5) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies[1][2][3][4][5][6][7][8][9].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-B0147S/Pefloxacin-d5-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Alternative Names | Pefloxacinium-d5 |
| CAS | 1228182-51-1 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 338.39 |
| Solubility | 10 mM in DMSO |
| Clinical Information | No Development Reported |
| Target | Antibiotic;Bacterial;DNA/RNA Synthesis;Isotope-Labeled Compounds;Parasite;Topoisomerase |