Oxaprozin - HY-B0808
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Catalog #
HY-B0808
Ab
26,00 €
Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-B0808/Oxaprozin-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Alternative Names | Oxaprozinum; Wy21743 |
| CAS | 21256-18-8 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 293.32 |
| Solubility | DMSO : ≥ 100 mg/mL |
| Clinical Information | Launched |
| Target | Akt;Apoptosis;COX;IKK;NF-κB |