Activin A, Human/Mouse/Rat (HEK293) - HY-P70311

Activin A, a multifunctional cytokine, is a member of TGF-β superfamily. Activin A first binds to the type II activin receptors (ActIIRA or ActRIIB) on the member surface, and then recruits and phosphorylates type I activin receptors (ActRI). Activin A primarily signal through SMAD2/3 proteins to regulate a variety of functions, including inflammation, fibrosis, and tumorigenesis[1]. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids (G310-S426).