Mouse anti-Proteinase Inhibitor 9, clone PI9-17 (Monoclonal) - MON2065

The human intracellular serpin proteinase inhibitor 9 (PI9) is the only human protein able to inhibit the activity of the serine protease granzyme B. Granzyme B is expressed by cytotoxic lymphocytes and induces rapid target cell apoptosis. PI9-17 Mab was selected after immunization with full length recombinant PI9 produced in Escherichia coli. No cross reactivity with other, homologous serpins (PI6, PI8 and PAI-2) was observed.