Why use C1s/C1-INH complex kits?

• Ready-to-use ELISA’s with a working time of 1 hour and 45 minutes

• Acute and reliable quantification of C1s/C1-INH complex or MASP-1/C1-INH complex

• Uses EDTA-plasma as input sample. No need for complement-preserved serum to assess early lectin pathway activation

 

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Why looking at C1-INH and its complexes? C1-INH administration is an approved common treatment for hereditary angioedema (HAE) and in clinical trials for:

• Covid-19 infections

• Prevention of rejection in kidney transplantation

• Traumatic brain injury and acute ischemic stroke

• Endotoxemia, sepsis, inflammation and multiple organ failure

• Application in end stage renal disease and chronic kidney disease

 

MASP-1/C1-INH

The concentration of MASP-1/C1-INH complex increases over time when the lectin pathway is activated in human serum, making the complex an indirect marker for ongoing lectin pathway activation

 

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Catalog #HK399-01 € 778,- (C1s/C1-INH, ELISA kit, 1 x 96 det.)

Catalog #HK399-02 € 1.257,- (C1s/C1-INH, ELISA kit, 2 x 96 det.)

Catalog # HK3001-01 € 778,- (MASP-1/C1-INH, ELISA kit, 1 x 96 det.)

Catalog # HK3001-02 € 1.257,- (MASP-1/C1-INH, ELISA kit, 2 x 96 det.)