PHD2/EGLN1 Rabbit mAb - A21252
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Catalog #
AB-A21252
Ab
135,00 €
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
| Isotype | IgG |
|---|---|
| Datasheet URL | https://abclonal.com/instructions/pdf/A21252 |
| Alternative Names | HPH2; PHD2; SM20; ECYT3; HALAH; HPH-2; HIFPH2; ZMYND6; C1orf12; HIF-PH2; N1 |
| Species | Human |
| Source | Rabbit |
| Purity | Affinity purification |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PHD2/EGLN1 (NP_071334.1). |
| Storage | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |