4-1BB/CD137 Rabbit mAb - A22167
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Catalog #
AB-A22167
Ab
115,00 €
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
| Isotype | IgG |
|---|---|
| Datasheet URL | https://abclonal.com/instructions/pdf/A22167 |
| Alternative Names | ILA; 4-1BB; CD137; CDw137; IMD109; 4-1BB/CD137 |
| Species | Human |
| Source | Rabbit |
| Purity | Affinity purification |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24-186 of human 4-1BB/CD137 (NP_001552.2). |
| Storage | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |