PIM1-IN-1 - HY-111552
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Catalog #
HY-111552
Ab
393,00 €
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-111552/PIM1-IN-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| CAS | 1417630-95-5 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 474.56 |
| Solubility | DMSO : 45 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Pim |
| Application: | Cancer-Kinase/protease |
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