(+)SHIN2 - HY-134978A
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Catalog #
HY-134978A
Ab
315,00 €
(+)SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor, whose target can be traced with 13C-serine. (+)SHIN2 increases survival in NOTCH1-driven mouse primary acute lymphoblastic leukemia (T-ALL) in vivo with a synergistic effect with Methotrexate (HY-14519)[1]. (+)SHIN2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-134978A/plus-SHIN2-DataSheet-MedChemExpress.pdf |
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Shipping | Room Temperature |
Application | Cancer-programmed cell death |
Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
MWT | 406.48 |
Solubility | 10 mM in DMSO |
Clinical Information | No Development Reported |
Pathway | Metabolic Enzyme/Protease |
Target | SHMT |
Application: | Cancer-programmed cell death |
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