(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane - HY-W021016

(+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano) ethane ((S,S)-Ph-BPE) is a chiral bisphosphine ligand and catalyst.\n\n(+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano) ethane acts as a chiral ligand in rhodium-catalyzed reductive hydroformylation of alkenyl boronic esters, enabling enantiodivergent synthesis of chiral γ-boryl alcohols. (+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano) ethane forms chiral nickel-phosphine complexes to mediate asymmetric hydrogenation of aliphatic γ- and δ-keto acids; protons promote substrate C=O bond activation and stereoselectivity control via hydrogen bonding. (+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano) ethane forms a monodentate nickel complex, which serves as the active species for asymmetric hydrogenation of aliphatic keto acids[1][2].