Peptidomimetic Library - PartA

Sizes available:

10 mM *30µl; 10 mM *50µl; 10 mM *100µl; 2*10 mM *100µl; 10 mM *250µl

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Peptidomimetics are compounds whose essential elements (pharmacophore) mimic a natural peptide or protein in 3D space and which retain the ability to interact with the biological target and produce the same biological effect. Peptidomimetics are designed to circumvent some of the problems associated with a natural peptide: e.g. stability against proteolysis (duration of activity) and poor bioavailability. Certain other properties, such as receptor selectivity or potency, often can be substantially improved. The design and synthesis of peptidomimetics are most important because of the dominant position peptide and protein-protein interactions play in molecular recognition and signaling, especially in living systems. Hence mimics have great potential in drug discovery. MCE Peptidomimetic Library contains 376 compounds including peptoid, α-helix mimetics, β-turn/sheets mimetics, etc. This library is an indispensable tool of structure-activity relationships in drug discovery. MCE Peptidomimetic Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 305 compounds supplied in 10 mM solution and 7 compounds supplied in 2 mM solution. For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.