Biotinylated Recombinant Human PTPRC/CD45R0/CD45 Protein - RP00395B
Catalog #
AB-RP00395B
580,00 €
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP00395B |
|---|---|
| Quantity | 100ug |
| Alternative Names | L-CA; CD45; T200; PTPRC; B220; CD45R; GP180; LCA; LY5; EC 3.1.3.48 |
| Species | Human |
| Source | HEK293 cells |
| Purity | >95%bySDS-PAGE；>95%byHPLC |
| Immunogen | Gln26--Lys416 |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |