Biotinylated Recombinant Human Siglec-10 (R119A) Protein - RP02585B
Catalog #
AB-RP02585B
710,00 €
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP02585B |
|---|---|
| Quantity | 100ug |
| Alternative Names | SLG2; SIGLEC10; MGC126774; PRO940 |
| Species | Human |
| Source | HEK293 cells |
| Purity | >95%byTris-BisPAGE;>95%bySEC-HPLC |
| Immunogen | Met17-Thr546 |
| Storage | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |